So my memory usage in Leopard is WAY down. I have Safari, DragThing, SSHKeychain, perl daemons, MySQL, Apache, MacCvsX, Eudora, BBEdit, iChat, Terminal
The biggest new memory pig is "helpdatad." Open Activity Monitor, sort by RSIZE, go into the Help menu of Activity Monitor, type into the new "Search" field, hit return, and watch helpdatad climb to the top. 180MB without breaking a sweat.
I killed the process and vowed to never type into that field again.