Learning new languages is frustrating, esp. when you're comparing them to what you already know: Perl.
Here's something I don't like about Python: the need for ending sub calls with (). I hate it.
Now, I know it's about something being 'callable' and without the params, you're returning the sub, not calling it. It's not intuitive for my brain. I don't like it.
Perl++ for never making me put () after method names or having to think about what it's doing.