I caught a repeat of the first episode of FLCL (Fooly Cooly) on Cartoon Network. FLCL is the most amusing, messed up, makes-no-sense, brilliant anime I've seen.
The first episode involves Naota being hit on by Mamimi, the girlfriend of his older brother who's off in America playing baseball. A Vespa driving alien, Horuko, then hits him on the head with a guitar which cause robots to come out of his head and battle. It's genius.