Slash Boxes
NOTE: use Perl; is on undef hiatus. You can read content, but you can't post it. More info will be forthcoming forthcomingly.

All the Perl that's Practical to Extract and Report

use Perl Log In

Log In

[ Create a new account ]

TorgoX (1933)


"Il est beau comme la retractilité des serres des oiseaux rapaces [...] et surtout, comme la rencontre fortuite sur une table de dissection d'une machine à coudre et d'un parapluie !" -- Lautréamont

Journal of TorgoX (1933)

Sunday July 20, 2003
01:02 PM

Uncertainties that limit and modify

[ #13574 ]
Dear Log,

«As a result, geneticists have borrowed from physics the analogy of a "black box" to represent the uncertainties of gene expression in living persons. [...] At least four technical terms have emerged in molecular biology in the effort to identify the uncertainties that limit and modify genetic determinism.

Penetrance refers to the variable degree to which a gene actually affects or dominates the life and behavior (phenotype) of the individual carrying that gene [...]

Epigenesis designates the mechanism that, at a certain stage of development, acts on networks of cells to supply variations from any predictable pattern [...]

Heterosis causes genes to affect each other in unexpected, nonadditive ways [...]

Developmental noise refers to random molecular events within cells during development, events that produce accumulating deviations from the norm [...]

All four terms refer to processes as yet little understood. [...]

All these considerations and black-box factors should mute the promises the HGP [Human Genome Project] tends to make about curing our individual and social ills. »

-- from chapter 6 of Roger Shattuck's book Forbidden Knowledge

The Fine Print: The following comments are owned by whoever posted them. We are not responsible for them in any way.
More | Login | Reply
Loading... please wait.