In response to a query from someone, I found myself explaining this (paraphrased):
You know I'm a Perl programmer. I teach the language, I sit on the Steering Committee of the Perl Foundation, I've been published on the language, yada, yada, yada. Despite all of that, I think the choice of the correct database is more important than the choice of programming language. Databases, even small ones, really are that important. Don't use MySQL.
If this guy said he was going to do all of his work in PHP (and he might), I'd be disappointed. If he settled for MySQL "just because", I'd be disgusted.