I just had a really cool idea to help with internationalisation when using AxKit... Basically you develop one site on one server but point different domain names at the same IP - so you might get www.fr.mysite.com, www.de.mysite.com etc etc.
Then you write a StyleChooser module for AxKit that picks the stylesheets based on the Host: header.
Of course you need to do all the other things you have to do in i18n like try your best to select based on Accept-Languages and so on. But this fits very nicely into AxKit's architecture.
It also solves a problem for me - what if companies want to re-sell your service, but change the look and feel of the "admin" site. You simply do the same as above, but implement a complete restyling rather than just i18n.